UTHealth Cryo-EM Core

About Our Core

The mission of Electron Cryo-Microscopy (Cryo-EM) Core Facility at UTHealth is to provide researchers access to the state-of-the-art cryo-EM resources and expertise. Our Cryo-EM Core has high-end cryo-EM instrumentation and expertise for near-atomic resolution single particle analysis of molecular structures (SPA cryo-EM) and for cellular structure determination by electron cryo-tomograpthy (cryo-ET). Our Cryo-EM core can advise and assist at all stages of the Cryo-EM/ET pipeline. Groups that anticipate high-usage of the Cryo-EM Core resources may consider having a user trained on the screening electron cryo-microscope, which could save on costs for core staff time.

The microscopes available in our facility are a Krios G3 with a Gatan BioQuantum energy filter with K2 camera and a Glacios Selectris X with a Falcon 4i camera.

To begin a request with our core, please select the "Schedule Equipment" tab and select the schedule for your preferred equipment.

Links and Resources

UTHealth Cryo-EM Core Facility Website

UTHealth Cryo-EM Training Resources

Acknowledging Cryo-EM Core

Any use of the resources at UTHealth Cryo-EM Core Facility requires acknowledgement of the resources in publications and presentations. 

Any work taking place on the Glacios has to acknowledge NIH S10ODO32204 grant. 

Example: Cryo-EM work (or Some of this cryo-EM work) was performed at the Cryo-EM Core Facility supported by the UTHealth Structural Biology Imaging Center at Houston and by grant from the NIH Office of the Director (1S10OD032204).  Titan Krios G3 subsidized by CPRIT Core Facility Award RP190602 was used for cryo-EM data acquisition in this work.

Location and hours of operation

Contacts