Welcome!
The Transgenic and Stem Cells Service Center was established in 1998 and since that time, it has generated over 750 new transgenic, knock-out and knock-in mouse animal models for investigators from UTHealth, as well as for scientists from numerous other academic institutions. The stem cell lines that have been derived in the laboratory are highly effective for the generation of knock-out/ knock-in mice and for cell differentiation studies. These cell lines are routinely used in the Core Facility and are also commercially distributed. In addition to the production, cryopreservation and re-derivation of genetically-engineered mice and rats, the services of the facility also include gene targeting, using ES cells or CRISPR/Cas9 genome editing and intellectual/technical support in different aspects of microsurgery, cell culture and stem cells research.
|
Monday - Friday 9am-5pm |
The University of Texas Health Science Center of Houston |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Aleksey Domozhirov |
Manager
|
713-500-2452
|
aleksey.y.domozhirov@uth.tmc.edu
|
SRB 430-01
|
| Price List |
| ► MICROINJECTION (3) | |||
| Name | Description | Price | |
|---|---|---|---|
| Transgenic Mice DNA/ BAC clones (per 2 days) microinjection only. |
PI responcible for mice purchase, shipping, caging, veterinary service – $4600.00 (estimate) |
UT System/In Network
$5,200.00
each
External $5,200.00 each |
|
| CRISPR/CAS9 services (per 2 days) microinjection only |
PI responcible for mice purchase, shipping, caging, veterinary service – $4600.00 (estimate) |
UT System/In Network
$5,200.00
each
|
|
| Knock-out mice, service to generate mice from ES cells (up to 2 clones). Microinjection only. |
PI responcible for mice purchase, shipping, caging, veterinary service – $4600.00 (estimate) |
UT System/In Network
$6,200.00
each
External $8,432.00 each |
|
| ► ES CELL SERVICES (2) | |||
| Name | Description | Price | |
| Derivation of MEF feeder cells |
UT System/In Network
$2,200.00
each
External $3,025.00 each |
||
| Expansion and cryopreservation |
UT System/In Network
$870.00
each
External $1,196.00 each |
||
| ► CRYOPRESERVATION (1) | |||
| Name | Description | Price | |
| Fertilized eggs |
UT System/In Network
$1,200.00
each
External $1,600.00 each |
||
| ► RE-DERIVATION (1) | |||
| Name | Description | Price | |
| Re-Derivation of mice from embryos |
PI responcible for mice purchase, shipping, caging, veterinary service – $1700.00 (estimate) |
UT System/In Network
$1,400.00
each
External $1,862.00 each |
|
| ► AVAILABLE CELL LINES (4) | |||
| Name | Description | Price | |
| MEF feeder cells (passage 3) 129/SvIMJ or C57BL6 |
UT System/In Network
$110.00
each
External $151.00 each |
||
| MEF feeder cells (passage 3) DR-4 |
UT System/In Network
$110.00
each
External $151.00 each |
||
| Mouse ES cells (1 vial, passage 11) 129/SVIM J |
UT System/In Network
$660.00
each
External $908.00 each |
||
| Mouse ES cells (1 vial, passage 11) C57/Bl/6 or BALB/c |
UT System/In Network
$990.00
each
External $1,361.00 each |
||
