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UTHealth Atomic Force Microscopy


Overview of Services


Atomic Force Microscopy (AFM) is a noninvasive technique that reproduces topographic images under physiological-like conditions. Scanning can be performed in air or in a liquid environment. A range of samples, from living cells down to single molecules, can be imaged. AFM is also an attractive tool for studying the dynamics of cellular endocytosis of nanovectors and the systemic response to biological processes.  An area of major interest is to determine the stiffness of a sample (Elastic Modulus). The elasticity of the cell membrane can vary between cell types as a function of growth, differentiation, disease or treatment. In addition, non-cellular structures can also be imaged.  
 
The Core uses a BioScope™ II atomic force microscope (Bruker Corporation; Santa Barbara, CA) that requires minimal sample preparation.  The BioScope™ II is integrated with a Nikon TE2000 inverted optical microscope to simultaneously acquire bright-field and fluorescence images of samples under study.

Leadership

   

Ana Maria Zaske, PhD       
Core Manager  
Phone: 713-486-5418
EmailAna.M.Zaske@uth.tmc.edu           

David Volk, PhD  
Core Director
Phone: 713-500-3611 
Email: David.Volk@uth.tmc.edu

Location and hours of operation

Hours Location

 

Monday - Friday            

9 am - 5 pm

 

Internal Medicine, UT-Health
1881 EAST RD,
room 3SCRB6.3728,
Houston, TX 77054

Links and Resources

  1. https://www.uth.edu/dotAsset/31cce68b-4480-4871-b803-b3da82eb4270.pdf

Contacts

Name Role Phone Email Location
Ana Maria Zaske, PhD
Manager
 
713-486-5418
 
Ana.M.Zaske@uth.tmc.edu
 
1881 EAST RD, 3SCRB6.3728, HOUSTON, TX 77054
 
David Volk
Director
 
713-500-3611
 
David.Volk@uth.tmc.edu
 
1825 Pressler, Room 330E,Houston, Texas 77030
 

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